Cinnamic acids and derivatives
Medchemexpress LLC 2-Hydroxycinnamic acid (Standard) | 614-60-8 | 98.7% | 164.16 | 50 MG
2-Hydroxycinnamic acid (Standard) | 614-60-8 | 98.7% | 164.16 | 50 MG
Medchemexpress LLC (4E)-7-(4-hydroxyphenyl)-1-phenylhept-4-en-3-one | 100667-52-5 | 97.0% | 280.36 g/mol | C19H20O2 | 5 MG
(4E)-7-(4-hydroxyphenyl)-1-phenylhept-4-en-3-one is a diarylheptanoid small-molecule for laboratory research and analytical applications. The compound is supplied as a solid with molecular formula C19H20O2, molecular weight 280.36 g/mol, and an analytical purity of 97.0% (NMR). Store protected from light at low temperatures; consult the certificate of analysis for batch-specific handling and stability information.
- Solid, white to off-white appearance.
- Molecular formula C19H20O2.
- Molecular weight 280.36 g/mol.
- Analytical purity 97.0% (NMR).
- Storage: keep container tightly sealed, protect from light; recommended -20°C for solid, in solvent -80°C for 6 months or -20°C for 1 month.
- Intended for research and analytical use only; not for human therapeutic use.
Selleck Chemical LLC Tyrphostin 9 S2895-25mg
Tyrphostin 9 (SF 6847 RG-50872) is firstly designed as an EGFR inhibitor with IC50 of 460 M but is also found to be more potent to PDGFR with IC50 of 0 5 M
Selleck Chemical LLC Tyrphostin AG 1296
Tyrphostin AG 1296 is an inhibitor of PDGFR with IC50 of 0 3-0 5 M no activity to EGFR Tyrphostin AG1296 inhibits FGFR and c-Kit with IC50 of 12 3 M and 1 8 M in Swiss 3T3 cells Tyrphostin AG1296 induces dramatic apoptosis in A375R cells
Medchemexpress LLC SAR405 R enantiomer | 1946010-79-2 | 99.9% | 443.85 | C19H21ClF3N5O2 | 10MM 1ML
SAR405 R enantiomer is the less active enantiomer of SAR405, a selective inhibitor of PIK3C3/Vps34, supplied for research use. It is offered as a ready-to-use 10 mM solution in DMSO or as a solid, and is used as a reference or control in studies of autophagy, vesicle trafficking, and related signaling pathways.
- Less active enantiomer of a PIK3C3/Vps34 inhibitor.
- High purity (~99.9%) for reliable experimental controls.
- Available as 10 mM solution in DMSO and multiple solid package sizes.
- Soluble in DMSO at 100 mg/mL; ultrasonication may be required.
- Storage: powder at -20°C or 4°C; in solvent at -80°C or -20°C.
- Intended for research use only, not for clinical applications.
Medchemexpress LLC SAR405 R enantiomer | 1946010-79-2 | 99.9% | 443.85 | C19H21ClF3N5O2 | 5MG
SAR405 R enantiomer is the less-active enantiomer of SAR405, a selective ATP-competitive inhibitor of class III PI3K (Vps34) used in research to profile autophagy and endosomal trafficking pathways. The compound is supplied as a high-purity solid and as a 10 mM solution in DMSO, with small pack sizes suitable for in vitro assays. Chemical identifiers: CAS 1946010-79-2; formula C19H21ClF3N5O2; molecular weight 443.85; purity 99.94%.
- Less-active enantiomer for control and stereochemistry studies.
- Selective inhibitor of PIK3C3/Vps34 for autophagy research.
- High purity suitable for biochemical and cell-based assays.
- Available as solid and as a 10 mM DMSO solution ready for use.
- Small pack sizes enable screening and dose-response experiments.
- Includes CAS and molecular data for compound tracking.
Selleck Chemical LLC (R)-(-)-JQ1 Enantiomer S2965-25mg
(R)-(-)-JQ1 Enantiomer is the stereoisomer of ( )-JQ1 ( )-JQ1 potently decreases expression of both BRD4 target genes whereas (R)-(-)-JQ1 Enantiomer has no effect
Medchemexpress LLC p-Coumaric acid | 501-98-4 | 164.16 | 1 ML
p-Coumaric acid (trans-4-Hydroxycinnamic acid) is an isomer of cinnamic acid with oral activity.
- Inhibits cell proliferation and promotes apoptosis.
- Exhibits antibacterial, anti-inflammatory, antioxidant, and anti-tumor activities.
- Can significantly inhibit the proliferation of human and mouse melanoma cells.
- Shows antibacterial activity against gram-negative and gram-positive bacteria, with MIC values for Escherichia coli, Streptococcus dysenteriae, and Salmonella typhimurium of 80, 10, and 20 μg/ml respectively.
- Has a protective effect on colon pretumor induced by 1,2 dimethylhydrazine (DMH) in rats.
- Alleviates nephrotoxicity induced by Doxorubicin by inhibiting oxidative stress, inflammation, and apoptosis.
Medchemexpress LLC M-coumaric acid | 588-30-7 | 99.8% | 164.16 | 1 ML
m-Coumaric acid is an endogenous metabolite and polyphenol that is formed from caffeic acid by gut microflora. It is a BBB-penetrant metabolite of chlorogenic acid and can stimulate cerebral nerves and evoke neurite outgrowth in hippocampal neuronal cells, promoting neuronal differentiation. It has also been shown to increase spontaneous locomotor activity in mice.
- Inhibits the oxidation of L-dopa by epidermis tyrosinase
- Attenuates non-catalytic protein glycosylation in retinas of diabetic rats
- Stimulates cerebral nerves in vitro
- Promotes neuronal differentiation
- Increases spontaneous locomotor activity
Medchemexpress LLC (E,E)-Bisdemethoxycurcumin (Standard) | 33171-05-0 | 98.5% | 308.33 | 1MG
(E,E)-Bisdemethoxycurcumin (Standard) is the analytical standard of (E,E)-Bisdemethoxycurcumin, designed for research and analytical applications. This curcumin derivative possesses anti-inflammatory and anticancer activities. It serves as a reference standard for assays and is commonly used in qualitative, quantitative, and methodological research experiments like HPLC, GC, and MS.
- Intended for research and analytical applications
- Possesses anti-inflammatory and anticancer activities
- Analytical standard grade for assays
- Suitable for HPLC, GC, and MS experiments
Selleck Chemical LLC Tyrphostin AG 879 S2816-25mg
Tyrphostin AG 879 potently inhibits HER2/ErbB2 with IC50 of 1 M 100- and 500-fold higher selective to ErbB2 than PDGFR and EGFR
Cayman Chemical Plnt TurmerIc CurcumIn 50g
A yellow pigment with diverse biological activities; inhibits NO production (IC50 = 6 μM) and reduces iNOS activity in LPS-stimulated RAW 264.7 cells; inhibits release of histamine and the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 from HMC-1 mast cells; decreases serum levels of histamine and TNF-α, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis; prevents ovalbumin-induced accumulation of 3-NT in mouse heart; reduces TPA-induced tumor formation in mouse skin (1-10 μmol); reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-NQO in rats
Matrix Scientific 4-(TRIFLUOROMETHYL)CINNAMI-25G
4-(Trifluoromethyl)cinnamic acid, 98%; 25g,C10H7F3O2, MFCD00002696, mw 216.16, [16642-92-5]
